Pet Recall Facts

Ingredients / Atipamezole

Atipamezole: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

3,934Total reports
2,641Dog reports
1,032Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19962
1997132
1998116
1999113
200090
200197
200288
200338
200484
200579
2006114
200782
2008114
2009124
2010150
2011109
2012138
2013128
2014124
2015135
2016134
2017144
2018122
2019125
2020117
2021103
2022135
2023245
2024299
2025318
2026134

Species named in reports

Dog2,641
Cat1,032
Not given191
Human12
Other10
Monkey6
Turtle6
Rabbit5

Signs reported after Atipamezole

Death570
INEFFECTIVE, REVERSAL467
Vomiting323
Lack of efficacy - NOS305
Lethargy (see also Central nervous system depression in Neurological)279
Hypersalivation269
Bradycardia248
Cardiac arrest210
Diarrhoea209
Sedation prolonged200
Anorexia187
Tachycardia171
Fever170
Accidental exposure149
Death by euthanasia148
No sign145
Ataxia142
Injection site swelling142
Panting141
Hypothermia138
Vocalisation138
Depression136
Not eating132
Hyperactivity126
Behavioural disorder NOS126

Breeds named in reports

Domestic Shorthair406
Dog (unknown)356
Retriever - Labrador309
Crossbred Canine/dog253
Domestic (unspecified)223
Shepherd Dog - German122
Retriever - Golden119
Cat (unknown)119
Terrier - Bull - American Pit83
Domestic Longhair76
Boxer (German Boxer)72
Rottweiler65
Shih Tzu64
Pit Bull62
Chihuahua60

Reported outcomes

Ongoing749
Recovered/Normal701
Died658
Outcome Unknown404
Euthanized99
Recovered with Sequela8

Report a problem to FDA