Pet Recall Facts

Ingredients / Grapiprant

Grapiprant: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

9,434Total reports
8,753Dog reports
15Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

20131
20151
20171,356
20181,289
20191,117
2020886
2021613
2022598
2023626
20241,414
20251,096
2026437

Species named in reports

Dog8,753
Not given652
Cat15
Human13
Pig1

Signs reported after Grapiprant

Vomiting1,557
Diarrhoea1,396
Lethargy (see also Central nervous system depression in Neurological)1,139
Lack of efficacy - NOS1,060
Death by euthanasia649
Elevated alanine aminotransferase (ALT)556
Not eating555
Decreased appetite503
Bloody diarrhoea421
Weight loss395
Elevated blood urea nitrogen (BUN)388
Tablets, Abnormal375
Anorexia359
Panting347
Seizure NOS347
Elevated creatinine324
Elevated serum alkaline phosphatase (SAP)322
Death313
Other abnormal test result NOS310
Ataxia306
Behavioural disorder NOS297
Loose stool252
Polydipsia242
Abnormal radiograph finding220
Polyuria220

Breeds named in reports

Dog (unknown)1,754
Retriever - Labrador1,554
Crossbred Canine/dog685
Retriever - Golden477
Shepherd Dog - German462
Poodle (unspecified)245
Shepherd Dog - Australian228
Collie - Border226
Chihuahua217
Pit Bull212
Siberian Husky206
Beagle190
Boxer (German Boxer)170
Terrier (unspecified)156
Shih Tzu149

Reported outcomes

Ongoing3,203
Outcome Unknown2,713
Recovered/Normal1,853
Euthanized649
Died332
Recovered with Sequela40

Report a problem to FDA