Pet Recall Facts

Ingredients / Hydrocortisone Aceponate

Hydrocortisone Aceponate: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

1,822Total reports
776Dog reports
19Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

2012120
2013250
2014227
2015191
20168
20171
20191
2020146
2021150
2022144
2023147
2024162
2025222
202653

Species named in reports

Not given1,018
Dog776
Cat19
Human9

Signs reported after Hydrocortisone Aceponate

Dispenser, Abnormal611
Uncoded sign311
Difficulty of Use305
Loss of hearing304
Product defect, product difficult to use/handle (see also Drug device difficult to use/handle)160
Hearing affected147
Administration device NOS, priming issue130
Product Defect, General110
Lack of efficacy - NOS75
Administration device NOS, abnormal73
Appearance, Abnormal56
Administration device NOS, malfunction55
Containers, Damaged47
Lethargy (see also Central nervous system depression in Neurological)35
Underfilling, Container35
Containers, Leaking32
Vomiting30
Deafness26
Lack of efficacy (bacteria) - NOS21
Head shake - ear disorder19
Pinnal erythema18
Product problem18
Behavioural disorder NOS17
Ataxia15
Head tilt - ear disorder15

Breeds named in reports

Retriever - Labrador83
Dog (unknown)69
Retriever - Golden42
Pug40
Pit Bull38
Terrier - Yorkshire37
Chihuahua31
Shepherd Dog - German29
Boxer (German Boxer)27
Maltese26
Shih Tzu22
Poodle - Standard20
Bulldog - French17
Poodle - Toy16
Beagle16

Reported outcomes

Outcome Unknown467
Recovered/Normal270
Recovered with Sequela34
Ongoing22
Euthanized9
Died4

Report a problem to FDA