Pet Recall Facts

Ingredients / Trilostane

Trilostane: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

12,198Total reports
11,910Dog reports
10Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

20041
20071
20081
200952
201077
2011219
2012566
2013632
2014686
2015710
2016832
2017920
20181,003
20191,057
2020971
2021940
2022856
2023809
2024800
2025684
2026381

Species named in reports

Dog11,910
Not given229
Human47
Cat10
Horse1
Other1

Signs reported after Trilostane

Lethargy (see also Central nervous system depression in Neurological)2,373
Vomiting2,024
Hyperkalaemia1,752
Elevated serum alkaline phosphatase (SAP)1,689
Weight loss1,497
Diarrhoea1,458
Underdose1,431
Elevated alanine aminotransferase (ALT)1,399
Elevated blood urea nitrogen (BUN)1,142
Decreased appetite1,123
Anorexia1,088
INEFFECTIVE, CUSHINGS978
Death by euthanasia914
Polydipsia859
Abnormal adrenocorticotropic hormone (ACTH) stimulation test855
Low sodium-potassium ratio (Na:K ratio)844
Other abnormal test result NOS817
Polyuria771
Lack of efficacy - NOS739
Hypoadrenocorticism691
Decreased urine concentration656
Urinary tract infection594
Panting569
Proteinuria556
Elevated gamma-glutamyl transferase (GGT)551

Breeds named in reports

Dog (unknown)1,609
Crossbred Canine/dog1,261
Retriever - Labrador832
Shih Tzu663
Chihuahua627
Beagle552
Maltese539
Terrier - Boston522
Terrier - Yorkshire507
Poodle - Miniature450
Dachshund - Miniature370
Terrier (unspecified)359
Boxer (German Boxer)337
Bichon Frise327
Dachshund - Standard Long-haired319

Reported outcomes

Outcome Unknown6,881
Recovered/Normal2,027
Ongoing1,384
Euthanized911
Died438
Recovered with Sequela84

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